Manchester United’s Champions League hopes suffered a setback as Brighton scored a dramatic 99th-minute penalty winner to keep their own European ambitions on track.

Alexis Mac Allister converted deep into injury time to settle a Premier League thriller at Amex Stadium.

United – in the fourth and final Champions League qualification spot – stay four points ahead of fifth-placed Liverpool, but now have only one game in hand.

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And Brighton deserved this victory for a relentless approach that finally gave them the breakthrough seconds from the end after Luke Shaw handled, the penalty awarded after a video assistant referee review.

Brighton, in sixth, are now only four points adrift of Liverpool, who have played two games more, and their celebrations at the final whistle contrasted sharply with the desolation of their defeat by United on penalties in the FA Cup semi-final at Wembley less than two weeks ago.

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Both sides had chances in a superb game, with Antony shooting wide for United in the opening seconds while both Marcus Rashford and Antony Martial forced Brighton keeper Jason Steele into important saves.

Brighton, fresh from the 6-0 thrashing of Wolves, played with the verve that has become their trademark. Kaoru Mitoma shot straight at David de Gea when clean through, and missed another good chance after the break, while Danny Welbeck was also off target with another presentable opening.

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The Seagulls turned up the pressure in stoppage time, De Gea saving superbly from Mac Allister and Pervis Etupinan before they finally made the breakthrough.